Hotels near Mayo Clinic, Rochester

Search and compare hotels near Mayo Clinic from hundreds of travel sites on HotelsCombined and save.

...and more

Learn why travellers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customie your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Refine Your Search

Star ratings
Guest Ratings
Amenities
Freebies
See all filters

Popular hotels near Mayo Clinic

Discover well-known properties in Mayo Clinic that are favoured by visitors more than others. There are 86 hotels in Mayo Clinic and price data was last updated on 13 March 2026. The average price for a hotel in Mayo Clinic is .
Enter your travel dates to find the best prices.
Filter by star ratings
All filters
20 2nd Avenue Southwest, Rochester, MN, United States
Hotel connected to the convention center in Rochester with 2 restaurants 2 restaurants, an indoor pool, and a 24-hour fitness center are available at this smoke-free hotel. WiFi in public areas is free. Additionally, a bar/lounge, a sauna, and a 24-hour business center are onsite. Housekeeping is available once per stay. Kahler Grand Hotel offers 552 air-conditioned accommodations with coffee/tea makers and hair dryers. Beds feature premium bedding. Televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include bathtubs or showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered once per stay and change of bedsheets can be requested. Housekeeping is provided on a limited basis. An indoor pool and a hot tub are on site. Other recreational amenities include a sauna and a 24-hour fitness center. Children under 17 years old are not allowed in the swimming pool, fitness facility, or hot tub without adult supervision. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
6.9
Good
1840 reviews
Location
1.5 km from city centre
S$ 163
9 3rd Avenue Northwest, Rochester, MN, United States
Hotel with an indoor pool, 3-minute walk to Mayo Clinic This smoke-free hotel features an indoor pool, a fitness center, and a coffee shop/cafe. Free self-serve breakfast and free WiFi in public areas are also provided. Other amenities include self parking, laundry facilities, and a 24-hour front desk. Housekeeping is available on request. Kahler Inn and Suites - Mayo Clinic Area offers 271 air-conditioned accommodations with coffee/tea makers and irons/ironing boards. Flat-screen televisions come with cable channels and pay movies. Rooms have partially open bathrooms. Bathrooms include showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Housekeeping is provided on request. Recreational amenities at the hotel include an indoor pool and a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
Airport shuttle
7.3
Good
2042 reviews
Location
1.6 km from city centre
S$ 165
225 South Broadway, Rochester, MN, United States
The Hilton Garden Inn Rochester Downtown is located in the heart of Rochester Minnesota with climate controlled skywalk access to the Mayo Clinic, University of Minnesota Rochester Shops at University Square, Mayo Civic Center, Government Center, numerous restaurants and theaters. Guests enjoy complimentary shuttle service to Mayo Clinic and deluxe accommodations. Rochester International Airport is 8 miles away with flights to Chicago and Minneapolis. Minneapolis / St. Paul International Airport is 80 miles away with frequent shuttle service. Interstate 90 is also 8 miles from downtown providing access from Madison, Chicago, and points east. Designed for both business and leisure travelers the hotel offers amenities such as free high-speed Internet with secure remote printing, microwave, refrigerator, coffee maker, ergonomic workstations. Guests can also enjoy the heated indoor pool, whirlpool, fitness center, and 24-hour business center. Hilton Honors Gold and Diamond members receive a food and beverage credit to use while on property and upgrades based on availability. For meetings and events the hotel provides 800 sq. ft. of flexible space for up to 70 people. Dining options include the Great American Grill / serving freshly prepared breakfasts, the Pavilion Pantry, stocked with convenient refrigerated and microwaveable items. Additional restaurants are within walking distance. When it is time to unwind, guests can relax at the pool or fitness center, explore nearby walking and biking paths just two blocks away, or visit Silver Lake Park, located one mile from the hotel.
Pool
Free Wi-Fi
8.4
Excellent
406 reviews
Location
1.4 km from city centre
S$ 175
10 East Center Street, Rochester, MN, United States
The Hilton Rochester Mayo Clinic Area is located in downtown Rochester two blocks from Mayo Clinic and one block from the Mayo Civic Center. Rochester International Airport is 8 miles away with flights to Chicago and Minneapolis. Minneapolis St. Paul International Airport is 80 miles away with frequent shuttle service. Interstate 90 is also 8 miles from downtown providing access from Madison, Chicago, and points east. The hotel offers spacious guest rooms and suites with Hilton bedding, work areas, seating, and free high speed internet. WiFi is available throughout and a Tech Lounge is located in the lobby. The fifth floor holds an indoor infinity pool, steam room, sauna, and outdoor rooftop terrace. Hilton Honors Gold members receive complimentary breakfast in the lounge and upgrades based on availability. Hilton Honors Diamond members receive complimentary lounge access and upgrades based on availability. Seven luxury suites are located on the top floor offering expansive accommodations with enhanced amenities. Guests in these suites have access to a dedicated concierge team providing personalized assistance with dining, transportation, and local arrangements for an elevated stay experience. The event center provides 24,000 sq. ft. of meeting and banquet space including two ballrooms with 19-foot ceilings, breakout rooms, and pre-function areas. Facilities feature modern audiovisual equipment and catering services for conferences, seminars, weddings, and receptions, with panoramic city views. The hotel connects to the city skyway system offering climate-controlled access to Mayo Clinic, Galleria at University Square mall, restaurants, the University of Minnesota Rochester campus, the Courthouse, and other downtown locations. Hilton Rochester Mayo Clinic Area combines a central location with contemporary design and personalized service for medical, business, and leisure travelers.
Pool
8.8
Excellent
190 reviews
Location
1.6 km from city centre
S$ 260
155 16th Avenue Southwest, Rochester, MN, United States
Hotel By St Mary's Hospital - Rochester Mayo Clinic Welcome to the Holiday Inn Express & Suites Rochester - Mayo Clinic Area hotel, located just 2.5 blocks west of St. Mary’s Hospital, and less than a mile from Mayo Clinic, the Gonda building, and the Eisenberg building. You'll find us on the corner of Hwy 52 and 2nd Street SW, making it easy to come and go as you please from our underground heated parking garage. Our hotel offers shuttle service to the hospital and clinic on weekdays for your convenience if you don't want to drive. And the Rochester International Airport is only 9 miles from us. The Rochester Holiday Inn Express is a great hotel for families while visiting the area. We are near some of Rochester's best attractions including the Mayo Civic Center, Silver Lake, Minnesota Children's Museum of Rochester, and the History Center of Olmsted County. After a long day, we hope you take the chance to visit one of the great local restaurants we have near the hotel like Canadian Honker, Cafe Presto, or Tonic that are just steps away from our door. We are even near popular chain restaurants including TGI Fridays, Olive Garden, and Famous Dave's. We hope your stay at the Holiday Inn Express Rochester, MN is a pleasant one.
Pool
Free Wi-Fi
Parking
8.2
Excellent
297 reviews
Location
1.8 km from city centre
S$ 157
470 17th Avenue Northwest, Rochester, MN, United States
One of Marriotts prestigious Diamond Award winning properties, the Fairfield by Marriott Rochester Mayo Clinic is ideally situated at the junction of US Hwy 52/63 and Hwy 14 West. Just 13 blocks from the world famous Mayo Clinics main campus, 7 blocks from Mayo Clinic's Saint Marys Hospital campus and minutes from IBM and Downtown Rochester. The hotel boasts many complimentary amenities for its guests including a full breakfast buffet, parking, first class shuttle service to the Mayo Clinic and St. Marys Hospital campuses, free high speed internet WiFi keeps you connected throughout the hotel and productive during your stay. The pool and fitness center helps you stay fit including a balanced breakfast buffet with several healthy choices. The City's 80 plus miles of connected walking and bike trails is accessible across from the hotel. After a long busy day relax and enjoy a fabulous meal at any of the neighboring restaurants with local fare.
Pool
Free Wi-Fi
Parking
8.8
Excellent
377 reviews
Location
2.5 km from city centre
S$ 157
101 1st Avenue Southwest, Rochester, MN, United States
Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via underground climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, running and several trails nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at our in new in house restaurant North Stone Kitchen. Business travelers, enjoy spacious guest rooms with work areas and Wi-Fi. All our guest rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury downtown Rochester at Rochester Marriott Mayo Clinic Area.
Pool
Free Wi-Fi
8.1
Excellent
297 reviews
Location
1.4 km from city centre
S$ 322
1211 2nd Street, Rochester, MN, United States
Hotel with free parking, steps from Mayo Clinic Hospital - Saint Marys Campus This smoke-free hotel features an indoor pool, a fitness center, and a 24-hour business center. Free full breakfast is provided, as well as free WiFi in public areas, free self parking, and a free area shuttle. Other amenities include a hot tub, coffee/tea in a common area, and a business center. Housekeeping is not available. Aspen Suites offers 82 air-conditioned accommodations with DVD players and safes. Accommodations offer separate sitting areas. Beds feature premium bedding. 32-inch flat-screen televisions come with premium cable channels. Accommodations at this 3-star hotel have kitchenettes with stovetops, microwaves, cookware/dishes/utensils, and dishwashers. Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include coffee/tea makers and irons/ironing boards. Housekeeping is offered daily and hair dryers can be requested. An indoor pool and a hot tub are on site. Other recreational amenities include a fitness center.
Pool
Free Wi-Fi
8.4
Excellent
174 reviews
Location
1.6 km from city centre
S$ 167
20 2nd Avenue Southwest, Rochester, MN, United States
Hotel connected to a shopping center in Rochester with 2 restaurants This smoke-free hotel features 2 restaurants, an indoor pool, and a fitness center. Free self-serve breakfast is provided, as well as free WiFi in public areas, free valet parking, and a free manager's reception. Other amenities include a bar/lounge, a coffee shop/cafe, and self parking. The Towers At Kahler Grand Hotel offers 44 accommodations with complimentary bottled water and coffee/tea makers. Each accommodation is individually furnished and decorated. Beds feature down comforters and premium bedding. Plasma televisions come with digital channels and pay movies. Bathrooms include showers, bathrobes, designer toiletries, and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include hair dryers and irons/ironing boards. A nightly turndown service is provided and housekeeping is offered daily. Recreational amenities at the hotel include an indoor pool and a fitness center.
Pool
Free Wi-Fi
7.9
Good
22 reviews
Location
1.5 km from city centre
S$ 514

Cheapest hotels near Mayo Clinic, Rochester

Discover affordable stays in Mayo Clinic that provide a quality experience without breaking the bank. Hotels in Mayo Clinic can be found for as low as S$ 80 per night. There is currently one property in Mayo Clinic that can be booked for this price. Baymont by Wyndham Rochester Mayo Clinic Area is one of the hotels that can be booked for the lowest price in Mayo Clinic. Price data was last updated on 13 March 2026
For those on a budget, these are the cheapest hotels available close to Mayo Clinic for the selected dates. If you have flexibility with arrival and departure, use the search form to compare prices for other dates.
1230 South Broadway, Rochester, MN, United States
0.9 km from city centre
Pool
Free Wi-Fi
Parking
S$ 80
Avg. per night
1215 2nd Street Southwest, Rochester, MN, United States
1.6 km from city centre
Free Wi-Fi
Parking
S$ 103
Avg. per night
435 16th Avenue Northwest, Rochester, MN, United States
2.3 km from city centre
Pool
Free Wi-Fi
Parking
S$ 114
Avg. per night
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
S$ 137
Avg. per night
1125 2nd Street Southwest, Rochester, MN, United States
1.5 km from city centre
Pool
Free Wi-Fi
Parking
S$ 138
Avg. per night
401 6th Street Southwest, Rochester, MN, United States
0.8 km from city centre
Pool
Free Wi-Fi
Parking
S$ 138
Avg. per night
165 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
S$ 156
Avg. per night
123 Fourth Ave. NW, Rochester, MN, United States
1.7 km from city centre
Free Wi-Fi
S$ 156
Avg. per night

Other accommodations in Mayo Clinic

Find the perfect hostel, theme hotel, or holiday rental for your stay in Mayo Clinic.
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
S$ 137
Avg. per night
441 West Center Street Northwest, Rochester, MN, United States
1.5 km from city centre
Free Wi-Fi
S$ 234
Avg. per night
225 South Broadway, Rochester, MN, United States
1.4 km from city centre
Pool
Free Wi-Fi
S$ 175
Avg. per night

Where to stay in Mayo Clinic

Explore different neighbourhoods and areas within Mayo Clinic to find the perfect location for your stay. Map data was last updated on 13 March 2026.
Whether you're visiting Mayo Clinic for leisure or business, utilize the map to find hotels close to your ideal location. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Mayo Clinic

Find useful tips and insights about staying in Mayo Clinic to help you make the most of your experience. FAQs were last updated on 13 March 2026.
  • What are the best hotels near Mayo Clinic?

    One of the most popular hotels near Mayo Clinic is Kahler Inn And Suites, which has been reviewed by 2,042 users and currently has a rating of 7.3/10. Other top-rated locations include SpringHill Suites by Marriott Mayo Clinic Area/Saint Marys and Hilton Garden Inn Rochester Downtown, which have received 8.4/10 and 8.4/10 ratings from our users, respectively.

  • What is a good hotel near Sentosa?

    Village Hotel Sentosa by Far East Hospitality is a popular hotel near Sentosa that is highly recommended, with a score of 8.6 across 4,703 reviews.

  • What is a good hotel in Mayo Clinic near Desaru Beach?

    Lotus Desaru Beach Resort & Spa is the hotel close to Desaru Beach that is most recommended by HotelsCombined users, with 4,691 reviews rating it at 8.4/10.

  • Is there a good hotel near Johor Bahru City Square?

    If you’re visiting Johor Bahru City Square then the nearby Amari Johor Bahru is a popular hotel with HotelsCombined users (6,030 reviews scoring it at an average 8.8/10).

  • How much is a cheap hotel near Mayo Clinic?

    Over the last 3 days, Mayo Clinic hotels have been found for as cheap as S$ 64/night in searches by HotelsCombined users.

  • What are the most popular landmarks to visit in Mayo Clinic?

    If your travel plans to Mayo Clinic are flexible, we recommend visiting at least one of the following most popular landmarks: Sentosa, Desaru Beach, or Johor Bahru City Square. Singapore is the city you should stay in if you want to visit Sentosa. Staying in Bandar Penawar is preferred if you want to visit Desaru Beach. To visit Johor Bahru City Square, it’s most convenient if you stay in Johor Bahru.

See more FAQs

Find better results for your stay in Mayo Clinic